Prebiotic synthesis of the major classes of iron–sulfur clusters

Chem. Sci., 2025, 16,4614-4624
DOI: 10.1039/D5SC00524H, Edge Article

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Simone Scintilla, Daniele Rossetto, Martin Clémancey, Julia Rendon, Antonio Ranieri, Graziano Guella, Michael Assfalg, Marco Borsari, Serge Gambarelli, Geneviève Blondin, Sheref S. Mansy
Greater concentrations of hydrosulfide lead to the prebiotic formation of higher nuclearity Fe–S peptides, culminating in a putative nitrogenase-like [6Fe–9S] cluster. Higher nuclearity clusters are more stable with lower reduction potential.
The content of this RSS Feed (c) The Royal Society of Chemistry