Identification of a Photoredox-Active Pt(IV) Complex that Induces Light-Mediated Cell Death

Chem. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5SC02879E, Edge Article

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Jevon Marsh, Lina Hacker, Sophie Alice Twigger, Jake Vickery, Shitong Huang, Claudia Almuzara Romero, Aaron Langston, Ismael Perez, Rebecca A Musgrave, Ester M Hammond, Adam Charles Sedgwick
We report the synthesis and characterisation of a series of fluorogenic Pt(IV) complexes – CarboBlue, OxaliBlue and CisBlue. These Pt(IV) complexes were identified as photoactive, oxidising biomolecules under light irradation…
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