The self-assembly of peptide amphiphiles (PAs) in aqueous solution yields nanoconstructs displaying a rich spectrum of sizes and morphologies, including micelles, fibers, and lamellar ribbons. The morphology impacts the bioactivity…
We present a manganese-mediated cross-electrophile coupling (XEC) that directly constructs C(sp)–Si bonds between alkynyl halides and chlorosilanes. By leveraging manganese as a bifunctional reductant/catalyst, this method enables a mild and…
Polyprenyl quinones, such as ubiquinone and menaquinone, are essential membrane-embedded redox cofactors that are involved in electron transport and found across all domains of life. However, their highly hydrophobic structure,…
Encapsulation of long-chain molecules is challenging because host molecules must capture entire guest structures through interactions at multiple points. Cavitand and capsule molecules bind long-chain guests within their cavities, where…
Per- and polyfluoroalkyl substances (PFAS) are highly persistent synthetic chemicals that pose severe environmental and health risks, prompting increasingly stringent regulations. The recent crises caused by PFAS contamination underscore the…
Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC90136G, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Rui Sun, Yang Yang, Xin Wu, Hua-Jin Zhai,…
Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC02378E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Yunzhu Meng, Tiantian Wei, Chenlin Zhang, Anqi…
In-brief analysis July 2, 2025 In 2024, the United States consumed about 94 quadrillion British thermal units (quads) of energy, a 1% increase from 2023,…
Macrocyclization and multiple backbone N-methylations can significantly improve the pharmacological properties of peptides. Since chemical synthesis of such compounds is often challenging, enzyme-based production platforms are an interesting option. Here,…
Complexes of uranium(II) remain extremely rare and their reactivity is practically unexplored. Here we report that the reduction of the heteroleptic bis-aryloxide U(III) complex , A, yields a rare and…
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