In this study, we present the first reported use of bioorthogonal click chemistry with rhenium-188 for radiolabelling of an anti-c-Met VHH Nanobody®. We employed a “chelate-then-click” strategy, wherein a bifunctional…
The native and tunable microscale fluid manipulation accessible within 3D-printed configurations can be a transformative tool in biosensing, promoting mass transport and sample mixing to boost assay performance. In this…
There is a growing interest in lanthanide complexes of unconventional oxidation states due primarily to their unique electronic structures and accompanying physicochemical properties. Herein likely the first examples of supramolecular…
Activity-based protein profiling (ABPP) is a unique proteomic tool for measuring the activity of enzymes in their cellular context, which has been well established for enzyme classes exhibiting a characteristic…
Inhibition of cGAS-STING overactivation has recently emerged as a promising strategy to counteract Alzheimer’s disease (AD). However, current cGAS-STING inhibitors as immunosuppressants suffer from instability, non-specific targeting, and innate immune…
Precise recognition of senescent cells is essential owing to their key role in various diseases, including aging and tumor suppression. Although senescence-associated β-galactosidase (SA-β-Gal) is widely used as a senescence…
Elucidating the timing and spatial distribution of DNA synthesis within cancer cells is vital for cancer diagnosis and targeted therapy. However, current probes stain nuclear acid relying on electrostatic interactions…
A novel propellane–nanoring hybrid, TPPTI-CMP, was synthesized by triply combining cyclo-meta-phenylene (CMP) with triperylenopropellane triimides (TPPTI). This structure features two CMP subunits which necessarily fill the voids of TPPTI and…
Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC00014A, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Yuanyuan Li, Chenyu Tao, Longhui Duan, Zhenhua…
In-brief analysis March 11, 2025 Data source: U.S. Energy Information Administration, Liquefaction Capacity File; trade pressNote: Commissioning refers to the stage in LNG…
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