Catalytic stereoselective synthesis of all-carbon tetra-substituted alkenes via Z-selective alkyne difunctionalization


Chem. Sci., 2025, Advance Article
DOI: 10.1039/D5SC00297D, Edge Article
Open Access Open Access
Prashant S. Shinde, Valmik S. Shinde, Magnus Rueping
We report a nickel-catalyzed cascade reaction leading to the arylation of an alkyne-induced acyl migration and the formation of all-carbon tetra-substituted alkenes in good yields with exclusive Z-selectivity.
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