Chem. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5SC01508A, Edge Article
Open Access Open Access
Yiming Ding, Xianwen Long, Jingwei Zhang, Qu Chunlei, Peng Wang, Xiaodong Yang, Pema-Tenzin Puno, Jun Deng
The first asymmetric total synthesis of penicifuranone A was accomplished in eight steps through an NHC-catalyzed umpolung strategy. Key features of the synthesis include an Al-Salen catalyzed asymmetric cyanosilylation to…
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