Bottom-up design of peptide shapes in water using oligomers of N-methyl-L/D-alanine

Chem. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5SC01483B, Edge Article

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jumpei Morimoto, Marin Yokomine, Yota Shiratori, Takumi Ueda, Takayuki Nakamuro, Kiyofumi Takaba, Saori Maki-Yonekura, Koji Umezawa, Koichiro Miyanishi, Yasuhiro Fukuda, Takumu Watanabe, Mayuko Suga, Ayumi Inayoshi, Takuya Yoshida, Wataru Mizukami, Koh Takeuchi, Koji Yonekura, Eiichi Nakamura, Shinsuke Sando
De novo design of peptide shapes is of great interest in biomolecular science since the local peptide shapes formed by a short peptide chain in the proteins are often key…
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