Radiotherapy is a widely used clinical treatment for locoregional cancers, but still faces with radiation resistance arising from abundant glutathione (GSH) and DNA damage repair (DDR). To overcome these self-defensive…
In this podcast, recorded at last week’s Pure//Accelerate 2025 event, we talk to Pure Storage’s chief technology officer (CTO), Rob Lee, to get a drill-down on use of key-value…
Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC03085D, Perspective Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Frank WeinholdSome recollections of how H-bonding and other…
Monofunctional platinum (Pt) complexes, characterized by their single reactive site capable of binding to DNA, exhibit distinct mechanisms of action compared to those of currently approved Pt-based chemotherapeutic drugs. Although…
Kseniia Petrova, a Harvard researcher, was detained in February after failing to declare scientific samples she was carrying into the country. Source link
The directive, in a memo issued Tuesday, came after two court rulings that questioned the Trump administration’s swift cuts to funding. Source link
(–)-Bedaquiline is considered to be one of the most promising therapeutic agents for tuberculosis over 50 years. However, there are limited general and highly stereocontrolled asymmetric synthetic methods available for…
Cyber security experts are urging operators of Citrix NetScaler Application Delivery Controller (ADC) and NetScaler Gateway appliances to get in front of a new vulnerability – quietly patched last…
Designing molecules with multiple properties of interest is a fundamental challenge in drug development. To tackle this, we have developed ScafVAE, an innovative scaffold-aware variational autoencoder designed for the in…
Health Secretary Robert F. Kennedy Jr. fired all 17 members of the panel and appointed eight new ones. Now, the board is down to just seven. Source link
admin