Why American therapy gets parents wrong
admin In India, we live with flawed parents without cutting ties. Western therapy sees things in black and white—and misses the cultural shades in between. Source link
March 2025
Machine learning-driven discovery of highly selective antifungal peptides containing non-canonical β-amino acids
Antimicrobial peptides (AMPs) are promising compounds for the treatment and prevention of multidrug-resistant infections because of their ability to directly disrupt microbial membranes, a mechanism that is less likely to…
Access to arynes from arenes via net dehydrogenation: scope, synthetic applications and mechanistic analysis
Arynes undergo a wide range of chemical transformations making them versatile reactive intermediates for organic synthesis. Access to arynes has long been dominated by pre-functionalised reagents, e.g., the venerable o-trimethylsilylaryl…
Multimeric, multivalent fusion carrier proteins for site-selective glycoconjugate vaccines simultaneously targeting Staphylococcus aureus and Pseudomonas aeruginosa
Staphylococcus aureus and Pseudomonas aeruginosa are major antimicrobial-resistant pathogens that often synergize in polymicrobial infections, such as chronic wound infections. These notorious and increasingly resistant bacteria contribute significantly to…
Effect of size, charge, and spin state on Hückel and Baird aromaticity in [N]annulenes
The Hückel and Baird rules provide a framework to understand the aromaticity of monocyclic π-conjugated molecules in their singlet ground state and lowest-lying triplet state, respectively, particularly in the context…
Facile synthesis of recyclable polythioimidocarbonates via aromatization-driven alternating copolymerization of para-quinone methide and isothiocyanates
Chem. Sci., 2025, 16,5493-5502DOI: 10.1039/D5SC00050E, Edge Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Wen-Dao Chu, Si-Yu Dan, Jie Zhan, Bo Chen,…
Unlocking the reactivity of the C–In bond: alkyl indium reagents as a source of radicals under photocatalytic conditions
Chem. Sci., 2025, 16,5623-5631DOI: 10.1039/D4SC08521C, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Anton A. Gladkov, Vitalij V. Levin, Demian Y.…
Advanced Software fined £3m over LockBit attack
The UK’s Information Commissioner’s Office (ICO) has today fined Advanced Computer Software Group – now known as OneAdvanced – £3.07m for cyber security failings that exacerbated the impact of…
Structural rigidity, thermochromism and piezochromism of layered hybrid perovskites containing an interdigitated organic bilayer
* Corresponding authors a Hybrid Materials Design, Institute for Materials Research (imo-imomec), Hasselt University, Martelarenlaan 42, B-3500 Hasselt,…
Photo-regulated disulfide crosslinking: a versatile approach to construct mucus-inspired hydrogels
The remarkable defensive ability of native mucus against pathogens has encouraged scientists to map its structure–-property correlation and its influence on immune defense mechanisms. However, its poorly defined structure, source-dependent…