Top 1,000 IT service providers in scope of UK cyber bill
admin The government has set out a series of ambitions and goals for the soon-to-be-introduced Cyber Security and Resilience Bill, including measures to better protect supply chain and operators of…
March 2025
Chemoproteomic identification of phosphohistidine acceptors: Posttranslational activity regulation of a key glycolytic enzyme
Histidine phosphorylation, an unconventional and understudied posttranslational modification, often involves phosphohistidine (pHis) “acceptor” proteins, which bind to pHis residues and undergo phosphotransfer from pHis. While the roles of pHis acceptors…
SIM Imaging of Bacterial Membrane Dynamics and Lipid Peroxidation During Photodynamic Inactivation with a Dual-Functional Activatable Probe
Photodynamic inactivation (PDI) has emerged as a promising antibacterial strategy that mitigates the risk of bacterial resistance. However, the precise morphological dynamics and mechanisms underlying bacterial cell death during PDI…
Polymerization-induced self-assembly enables access to diverse highly ordered structures through kinetic and thermodynamic pathways
Polymerization-induced self-assembly (PISA) has emerged as a powerful technique for generating microphase-separated structures, but research has primarily focused on systems exhibiting “disordered” structures. Here, we demonstrate the facile construction of…
IMPRESSION Generation 2 – Accurate, fast and generalised neural network model for predicting NMR parameters in place of DFT.
Predicting 3D-aware Nuclear Magnetic Resonance (NMR) properties is critical for determining the 3D structure and dynamics, both stereochemical and conformational, of molecules in solution. Existing tools for such predictions are…
Why the Right Still Embraces Ivermectin
Joe Grinsteiner is a gregarious online personality who touts the anti-parasitic drug ivermectin. In a recent Facebook video, he produced a tube of veterinary-grade ivermectin paste — the kind made…
Reassessing UK law enforcement data adequacy
The UK government says reforms to police data protection rules will help simplify law enforcement data processing, but critics argue the changes will lower protection to the point where…
Do weaker solvation effects mean better performance of electrolytes for lithium metal batteries?
The design of novel electrolytes is crucial for ensuring the practical application of high-voltage lithium metal batteries (LMBs). Weakly solvating electrolytes (WSEs), achieved by reducing the solvent’s solvation ability, have…
UK law enforcement data adequacy at risk
The UK government has introduced its Data Use and Access Bill (DUAB) to Parliament, but proposed reforms to police data protection rules could undermine law enforcement data adequacy with…
An Implantable Ionic Liquid-Gel Microelectrode for In Vivo Monitoring of K+ Levels in the Living Rat Brain
The exploration of new interfaces for in vivo analysis holds great promise for electrochemical acquirement of chemical signals involved in brain events. In this study, we designed and created an…